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Title:	O uso da ventilação mecânica não invasiva em pediatria: uma revisão sistemática com metanálise
Authors:	Immaginario, Mariana Badke Neves
metadata.dc.contributor:	Boëchat, Giovanna Assis Pereira
Keywords:	Insuficiência respiratória - Ventilação pulmonar - Crianças - Adolescentes
Issue Date:	5-Feb-2013
Abstract:	Objective: To determine the effectiveness and safety of non-invasive positive pressure ventilation (NIPPV) compared to standard therapy in children. Hypothesis: the use of non-invasive ventilation in children is safe and effective. Study Design: Systematic review of randomized clinical trials or quasi-randomized clinical trials, comparing the use of NIPPV to standard therapy in pediatric patients. Patient Selection: Only studies with patients aged one month to eighteen years were included in this review. Methodology: We included only randomized controlled trials or quasi-randomized clinical trials with or without blinding, searched the MEDLINE, LILACS, SciSearch, database of controlled trials of the Cochrane Collaboration and personal communication with the authors. The outcome measures were need for endotracheal intubation, ventilation time, hospital mortality, length of hospital stay, adverse events, changes in vital signs, oxygenation and ventilation. Results: Of the 1055 publications found, 5 were included in this review, one with children with asthma, two with bronchiolitis, one with lower airway obstruction and one with acute respiratory failure, involving a total of 133 patients. The non-invasive ventilation caused a low risk for treatment failure and endotracheal intubation. Only four of the one hundred and thirty-three patients died. Conclusions: The included results of these studies did not show clearly the effectiveness and safety of the use of NIPPV as adjunctive therapy in pediatric. This may be due to the small number of studies found that in the pediatric population is very limited.
URI:	https://repositorio.uvv.br//handle/123456789/227
Appears in Collections:	Dissertação de Mestrado

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